New research brings encouraging news to people who suffer from highly fatal brain tumors called glioblastomas. Researchers at UT Southwestern Medical Center have discovered that blocking critical DNA repair mechanisms could improve the effectiveness of radiation therapy for these specific brain tumors.
DNA must be repaired for tumors to keep growing. Radiation therapy causes double strand breaks in that DNA – blocking glioblastomas which are highly resistant to radiation therapy. Blocking the growth of those tumors or slowing the progression of this disease can extend a patient’s survival.
The findings were published in a recent issue of Clinical Cancer Research. Additionally, researchers believe combining RT with a drug called NVP-BEZ235 would significantly improve survival rates.
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