A study published in the World Journal of Surgery reveals a major development in identifying and treating a rare form of thyroid cancer. In a scientific first, the fusion of two genes, ALK and EML4, has been identified as the genetic driver in papillary thyroid cancer.
The tumor cells of a 62-year-old patient were studied and a comparison of the tumor DNA to the patient’s normal DNA found 57 mutations in 55 genes of the cancer genome. The research also found the rearrangement between two genes. The fusion and the relocation allowed scientists to determine this was the genetic drive of the patient’s cancer.
These groundbreaking findings allowed scientists to recommend a certain course of treatment for the patient that lead to halting the progression of the disease for 6-months. These findings could ultimately do the same for other patients.
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