Four new genes added to the ‘inherited breast cancer’ risk list

Most of us have heard of the abnormal genes inherited in certain breast cancer cases called BRCA1 and BRCA2 genes. Well now researchers have located four more genes that increase the risk of breast cancer when mutated.

Researchers at Huntsman Cancer Institute at the University of Utah have discovered four new gene mutations that increase inherited breast cancer susceptibilities. These genes are called RINT1, MRE11A, RAD50 and NBN to the growing list of higher risk genes.

Before a cell becomes cancerous, a number of mistakes need to be present in its genetic code. These mistakes are referred to as mutations and being born with a mutation could increase an individual’s risk of developing breast cancer.

RINT1 was detected to additionally increase risk for a broad spectrum of gastrointestinal and gynecological cancers in families that carry the gene mutation.

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